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Conjugated proteins were detected by an enhanced chemiluminescent immunoblotting detection system, the ChemiDoc Touch Imaging System (BIO RAD, CA, USA) was performed

Combining other metabolic conditions, such as diabetes and obesity, with an imbalanced fat metabolismwhich is a pro-atherosclerotic factormay significantly increase the risk of cardiovascular disease (CVD), especially in people with CKD (145)

The primer/probe targets were Agrp (Mm00475829_g1), Glp1r (Mm00445292_m1), Insr (Mm01211875_m1), Lepr (Mm00440181_m1), Mc4r (Mm00457483_s1), and Pomc (Mm00435874_m1)

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Podczas fermentacji bonnika rozpuszczalnego przez bakterie jelitowe powstaj krtkoacuchowe kwasy tuszczowe (SCFA), ktre zwikszaj wydzielanie GLP-1 w okrnicy